Progressive Supranuclear Palsy (PSP, Steele-Richardson-Olszewski Syndrome) is a neurodegenerative disease with loss of neurons in the basal ganglia (pallidum, substantia nigra, subthalamic nucleus) and brainstem. The most important clinical signs are postural instability and a vertical gaze palsy combined with parkinsonian symptoms.
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- PSP Pathology Case Clinical history, specimens and microscopic description.
- ClinicalTrials.gov Active clinical PSP therapy study.
- Society for Progressive Supranuclear Palsy: Some Answers Frequently asked questions about symptoms, diagnosis, treatment, and research.
- NORD: Progressive Supranuclear Palsy Information from the National Organization for Rare Disorders about progressive supranuclear palsy.
- WebMD Health: Progressive Supranuclear Palsy Causes, risk factors, signs and symptoms, therapy and prognosis of PSP.
- PSP-Europe Association Disease and research information and a PSP newsletter.
- Progressive Supranuclear Palsy National Institute of Neurological Disorders and Stroke fact sheet.
- NHS Choices: Progressive Supranuclear Palsy Provides information on this condition in which increasing numbers of brain cells become damaged over time. Includes details of symptoms, causes, diagnosis, treatment and complications.
- eMedicine Health - Progressive Supranuclear Palsy Consumer health resource center providing information on the causes, symptoms, and treatment of PSP, a rare degenerative disease of the brain.