Alpers' disease or Alpers' Progressive Infantile Poliodystrophy is a rare, progressive neurodegenerative disease of the brain. It is thought to be an autosomal recessive disorder and usually affects children under the age of 5. Convulsions mark the onset of the disease, followed by dementia, spasticity and monoclonus. The untreatable disease is fatal and patients usually die a few months after disease onset.
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- NORD: Alpers Disease A brief description along with alternate name, followed by a list of resources for further information.
- Alpers' Disease Information sheet compiled by NINDS.
- MedicineNet.com An Alpers' disease article with some general information.