POEMS syndrome is an extremely rare multisystem disorder. POEMS is an acronym that stands for (P)olyneuropathy, disease affecting many nerves; (O)rganomegaly, abnormal enlargement of an organ; (E)ndocrinoapthy, disease affecting certain hormone-producing glands that help to regulate the rate of growth, sexual development, and certain metabolic functions (endocrine system); (M)onoclonal gammopathy or M proteins; and (S)kin defects.
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- NORD: POEMS Syndrome Offers the synonyms, a general discussion and resources.
- Patient UK: POEMS Syndrome Factsheet on this condition, including its epidemiology, presentation, clinical features, complications, investigation, management and prognosis.