With respect to this category, a "center" is an institute or facility involved in the study, prevention, or treatment of stroke--a sudden interruption of blood flow to a region of the brain, caused by a blockage or rupture in a vessel supplying that region.
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- Scripps Brain and Stroke Research and Treatment Center Center of Excellence focusing on the prevention and treatment of stroke and other disorders of the brain. Located in San Diego, California.
- Hartford Hospital Stroke Center Connecticut-based center, founded to increase awareness of stroke, deliver coordinated therapy, and develop new modalities for care. Certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.
- Stanford University Stroke Center Research and treatment facility, certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations. Located in Palo Alto, California, the Center's online resources include a consumer-oriented guide to stroke, assessment scales, and descriptions of ongoing clinical trials.
- Stroke Centers of Continuum Health Partners New York City–area stroke specialists, available around the clock to provide emergent and in-patient care at Beth Israel Medical Center, Roosevelt and St. Luke's Hospitals, and Long Island College Hospital.
- UCLA Stroke Center Providing diagnostic and therapeutic care of patients with disorders of the brain and spinal-cord vasculature. Certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.
- UC Irvine Health: Comprehensive Stroke & Cerebrovascular Center Orange, California center offering advanced stroke care programs. Certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.
- Nebraska Stroke Center Home of Nebraska Medical Center's multidisciplinary stroke team, Nebraska Stroke Center is prepared to provide care 24 hours a day and is certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.
- Froedtert & Medical College Stroke Program Providing coordinated services to cover the entire spectrum of care for stroke patients in the Milwaukee Metro Region. Certified as a Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations.