Commercial organizations whose primary interest is to develop gene therapies for clinical use.
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- Cobra Biomanufacturing Contract manufacturing organisation focusing on the production of protein, viral and DNA-based therapeutics at cGMP grade.
- Oxford Biomedica Focuses on developing gene transfer technologies for human gene therapy, gene-based immunotherapy, and gene-based drug discovery for cancer, AIDS, neurodegenerative and cardiovascular disease.
- BioVex Biotechnology company developing a new class of biologics for the treatment of cancer and prevention of infectious disease. OncoVEX is a cancer destroying virus technology and ImmunoVEX is a vaccine for genital herpes.
- GenVec An emerging biopharmaceutical company developing novel gene therapies for diseases where local delivery of a therapeutic gene has potential benefits over currently available treatments. New product development initiatives have been formalized for coronary artery disease with BioBypass angiogen, restenosis prevention and cancer.
- Transgene S.A. Gene therapy company based in France is developing products for cancer and cystic fibrosis. Vector platforms include adenovirus, retrovirus, vaccinia virus, cellular and synthetic vectors.
- Henogen A GMP biomanufacturing company located in Belgium, able to produce, purify and aseptically fill clinical batches of therapeutic proteins, monoclonal antibodies, plasmid DNA, vaccinal viruses or viral vectors for gene therapy.
- Puresyn, Inc. Develops separation and purification processes for manufacturing gene delivery products such as supercoiled plasmids, synthetic oligonucleotides, recombinant adenovirus and adeno-associated virus.