XMRV is a human retrovirus discovered in cancerous prostate tissues in 2006 by Dr. Robert Silverman, a cancer biologist at the Cleveland Clinic. In October, 2009, Dr. Silverman along with other researchers reported finding the virus in the majority of patients they studied who have Chronic Fatigue Syndrome. Studies in the Netherlands and the United Kingdom were unable to replicate their findings.
XMRV is a descriptive name:X - Xenotropic (a virus that is found benignly in cells of one animal species but only infects different species)
M - Murine leukemia, the parent virus
RV - Related Virus
Related categories 2
Sites 14
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- British Medical Journal: Chronic Fatigue Syndrome and Human Retrovirus XMRV Referenced article about the findings of different studies.
- Prevalence of Xenotropic Murine Leukaemia Virus-related Virus in Patients with Chronic Fatigue Syndrome in the Netherlands Report on a retrospective analysis that failed to show the presence of XMRV.
- PNAS: A New Human Retrovirus Associated with Prostate Cancer Referenced article on the connection found between XMRV and prostate cancer.
- PNAS: XMRV is Present in Malignant Prostatic Epithelium and is Associated with Prostate Cancer Research findings on the association between XMRV and prostate cancer, including some differences from previous research which indicate more people may be at risk.
- ScienceDaily: Correlation Between XMRV and Prostate Cancer: Novel Retrovirus Diagnostic Test Developed Report about the successful development of an experimental clinical test for XMRV by researchers at Emory University.
- Urology: XMRV Infection in Patients With Prostate Cancer: Novel Serologic Assay and Correlation With PCR and FISH Full text of the report from Emory University on the development of the serum test to identify XMRV infection.
- Wall Street Journal: Potential Risk to Blood Supply Probed Article on the public-health response to XMRV.
- Medscape Medical News: Controversy Continues on Whether XMRV Retrovirus Contributes to Chronic Fatigue Syndrome Addressing the need for standardization in testing and the possibility of blood banks to refuse donations from people with CFS.
- WSJ.com: Further Evidence of an XMRV-Chronic Fatigue Syndrome Connection? A report that a respected NIH expert supported an association between the XMRV virus and chronic fatigue syndrome during a closed workshop on blood transfusion in May.
- CDC: XMRV Overview and questions and answers.
- This Week in Virology: XMRV with Professor Stephen Goff Netcast of virologist Vincent Racaniello speaking with retrovirus researcher Stephen Vincent about the origin of XMRV and its association with disease.
- Retrovirology: Detection of a Gammaretrovirus, XMRV, in the Human Population Questions concerning the detection of XMRV and implications for xenotransplantation.
- Retrovirology: Absence of Xenotropic Murine Leukaemia Virus-related Virus in UK Patients with Chronic Fatigue Syndrome Full text of a study that did not find XMRV in CFS patients in the United Kingdom.
- Science: Detection of an Infectious Retrovirus, XMRV, in Blood Cells of Patients with Chronic Fatigue Syndrome Abstract of the report with links to related articles and research.