The S-Plus system is the sole, official, commercial implementation of Bell Laboratories S. Since about 1993, the only Bell Labs license for S has been an exclusive license, with the makers of S-Plus, MathSoft Corp. S software from Bell Labs research is sent to MathSoft, which provides modifications and additions to make S-Plus and other software products, and support, education, and related services.
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- ESS: Emacs Speaks Statistics Package for GNU Emacs, provides command-line, editing and transcript support for S-Plus on Unix, Windows.
- Applied Statistics in the Pharmaceutical Industry: Millard and Krause Book describing the drug development process illustrating the practical problems and the statistical approaches to tackling them using S-Plus.